林凤鸣

发布者：张怡茹发布时间：2020-09-04浏览次数：16885




教授，博士生导师。主要从事合成生物、系统生物学、生物医用材料等领域的研究。至今在Chemical Engineering Journal、Small Structure、mBio、Nanoscale、Biotechnology for Biofuels等杂志发表SCI论文55篇，其中通讯/一作45篇，发表文章总引用次数2200多次。授权专利11项。主持国家自然科学青年基金和面上项目基金。参与973、863等重大科技项目多项。目前的主要研究方向有（1）微生物蛋白质的机理研究和应用；（2）生物质碳点的合成和应用；（3）抗菌抗癌纳米药物研发。

每年招收博士后，博士生，硕士生，本科毕业设计。联系方式：linfengming@seu.edu.cn。

 

工作教育经历：

2023/5-至今， 东南大学，生医学院，教授

2014/9-2023/4，东南大学，生医学院，副教授

2011/9-2014/8, 美国密歇根大学，化工系和化学系，博士后

2005/9-2011/6，天津大学，制药工程，博士，元英进 

2009/9-2011/6，美国密歇根大学，化学工程系，联合培养，Xiaoxia Nina Lin

2001/9-2005/9，天津大学，制药工程，学士

 

已发表的论文：

  1. （1）Samran Durrani, Jie Zhang, Faisal Durrani, Zihao Wang , Mukramin, Ke-Fei Xu, Haiyan Wang, Haroon Khan, Fu-Gen Wu, Fengming Lin*. Triple channel fluorescence Na-Ca-Cl-doped carbon dots for erythrosine detection in food samples and living cells. Journal of Molecular Structure, 2025, 139934.  (IF: 4.9; 2区)

  2. （2）Haiyan Wang, Xiaotong Shi, Liujie Huo, Jing Tu, Chengcheng Li, Fu-Gen Wu, Fengming Lin*. The discovery of novel ER-localized cellobiose transporters involved in cellulase biosynthesis in Trichoderma reesei. Journal of Basic Microbiology, 2024, e2400573.(IF: 3.5; 4区)

  3. （3）Jie Zhang, Barbar Khan, Funing Zhang, Samran Durrani, Fu-Gem Wu, Fengming Lin*. Natural outer membrane vesicles from Serratia marcescens for inherent and biocompatible anti-microbial photodynamic therapy. Chemical Engineering Journal, 2024,502. (IF: 13.4; 1区)

  4. （4）Babar Khan, Jie Zhang, Samran Durrani, Haiyan Wang, Ali Nawaz, Faisal Durrani, Yonghao Ye, Fu-Gen Wu, Fengming Lin*. Carbon-dots-mediated improvement of antimicrobial activity of natural products. ACS Applied Materials & Interfaces 2024, 16, 47257−47269. (IF: 8.5; 2区)

  5. （5）Ai-Ping Pang, Haiyan Wang, Yongsheng Luo, Funing Zhang, Fu-Gen Wu, Zhihua Zhou, Zuhong Lu*, Fengming Lin*. Investigating the cellular functions of ?-glucosidases for synthesis of lignocellulose-degrading enzymes in Trichoderma reesei, Engineering Microbiology, 2023, 3, 1005.

  6. （6）Haiyan Wang, Ai-Ping Pang, Bingzhi Li, Liujie Huo, Fu-Gen Wu, Fengming Lin*. Intracellular sugar transporters facilitate cellulase synthesis in Trichoderma reesei using lactose. Biomolecules, 2023, 13, 295. (IF: 5.5; 2区)

  7. （7）Zihuayuan Yang, Jie Zhang, Fu-Gen Wu, Fengming Lin*. Structural characterization, functional profiling, and mechanism study of four antimicrobial peptides for antibacterial and anticancer applications. Langmuir 2023, 39, 2161−2170. (3.9; 3区)

  8. （8）Samran Durrani, Jie Zhang, Mukramin, Haiyan Wang, Zihao Wang, Latif Ullah Khan, Funing Zhang, Faisal Durrani, Fu-Gen Wu, and Fengming Lin*. Biomass-based carbon dots for Fe3+ and adenosine triphosphate detection in mitochondria. ACS Applied Nano Materials, 2023, 6, 1, 76–85. (IF: 5.9; 2区)

  9. （9）Samran Durrani, Zihuayuan Yang, Jie Zhang, Zihao Wang, Haiyan Wang, Faran Durrani, Fu-Gen Wu, Fengming Lin*.Nucleus-targeting pH-responsive carbon dots for fast nucleus pH detection. Talanta, 2023, 152:123855. (IF: 6.5; 2区)

  10. （10）Zihuayuan Yang, Xin Hu, Funing Zhang, Samran Durrani, Jie Zhang, Ai-Ping Pang, Yichen Gao, Fu-Gen Wu, Fengming Lin*. Chitosan-modified fluorescent dye for simple, fast, and in-situ measurement of fungal cell growth in the presence of insoluble compounds. FEMS Microbiology Letters, 2022, 369,1, fnac118. (IF: 2.8; 4区)

  11. （11）Haiyan Wang, Ai-Ping Pang, Wei Wang, Bingzhi Li, Chengcheng Li,Fu-Gen Wu, Fengming Lin*. Discovery of ER-localized sugar transporters for cellulase production with lac1 being essential. Biotechnology for Biofuels and Bioproducts, 2022, 15: 132.  (IF: 7.7; 1区)

  12. （12）Jie Zhang, Funing Zhang, Xin Hu, Jing Yang, Haiyan Wang, Samran Durrani, Fu-Gen Wu, Fengming Lin*. Self-assembly and disassembly of glycol chitosan/photosensitizer nano-micelles for antibacterial photodynamic therapy. ACS Applied Polymer Materials, 2022, 4, 8665−867. (IF: 4.8; 2区)

  13. （13）Fengming Lin, Chenyang Jia, and Fu-Gen Wu*. Intracellular enzyme-instructed self-assembly of peptides (IEISAP) for biomedical applications. Molecules, 2022, 27, 6557. (IF: 4.9; 2区)

  14. （14）Fengming Lin, Zihao Wang and Fu-Gen Wu*. Carbon dots for killing microorganisms: An update since 2019. Pharmaceuticals, 2022, 15, 1236. (IF: 5.2; 2区)

  15. （15）Chengcheng Li, Ruihan Gu, Fengming Lin*, Huining Xiao*. Sorbicillinoids hyperproduction without affecting the cellulosic enzyme production in Trichoderma reesei JNTR5. Biotechnology for Biofuels, 2022, 15: 85. (IF: 7.7; 1区)

  16. （16）Fengming Lin, Cheyang Jia, Fu-Gen Wu*, Carbon dots for intracellular sensing. Small Structures, 2022, 3, 2200033. (IF: 11.3)

  17. （17）Ai-Ping Pang, Yongsheng Luo, Xin Hu, Funing Zhang, Haiyan Wang, Yichen Gao, Samran Durrani, Chengcheng Li, Xiaotong Shi, Fu-Gen Wu, Bing-Zhi Li, Zuhong Lu*, Fengming Lin*. Transmembrane transport process and endoplasmic reticulum function facilitate the role of gene cel1b in cellulase production of Trichoderma reesei. Microbial Cell Factories, 2022. (IF: 6.4; 2区)

  18. （18）Yichen Gao, Ai-Ping Pang, Leyao Ma, Haiyan Wang, Samran Durrani, Bingzhi Li, Fu-Gen Wu, Fengming Lin*. Intron retention coupled with nonsense-mediated decay is involved in cellulase biosynthesis in cellulolytic fungi. Biotechnology for Biofuels, 2022, 15: 53.  (IF:7.7; 1区)

  19. （19）Samran Durrani, Jie Zhang, Ai-Ping Pang, Yichen Gao, Tian-Yu Wang, Haiyan Wang, Fu-Gen Wu, Fengming Lin*. Carbon dots for multicolor cell imaging and ultra-sensitive detection of multiple ions in living cells: one stone for multiple birds. Environmental Research, 2022, 212:1113260 (IF: 8.4; 2区)

  20. （20）Samran Durrani, Jie Zhang , Zihuayuan Yang, Ai-Ping Pang, Jia Zeng, Sayed Mir Sayed, Adeel Khan, Yaqin Zhang, Fu-Gen Wu, Fengming Lin*. Plant-derived Ca, N, S-Doped carbon dots for fast universal cell imaging and intracellular Congo red detection. Analytica Chimica Acta, 2022, 339672. (IF: 6.9; 1区)

  21. （21）Jie Zhang, Zihuayuan Yang, Yan-Hong Li, Samran Durrani, Ai-Ping Pang, Yichen Gao, Fu-Gen Wu, Fengming Lin*. Super stable chitosan-based nanoparticles for broad-spectrum antimicrobial photodynamic therapy. ACS Applied Polymer Materials, 2022, 4:425–434. (IF: 4.8; 2区)

  22. （22）Ai-Ping Pang, Funing Zhang, Xin Hu, Yongsheng Luo, Haiyan Wang, Samran Durrani, Fu-Gen Wu, Bing-Zhi Li, Zhihua Zhou, Zuhong Lu*, Fengming Lin*. Glutamine involvement in nitrogen regulation of cellulase production in fungi. Biotechnology for Biofuels, 2021, 14:199.  (IF: 7.7; 1区)

  23. （23）Ai-Ping Pang, Haiyan Wang, Funing Zhang, Xin Hu, Fu-Gen Wu, Zhihua Zhou, Wei Wang, Zuhong Lu*, Fengming Lin*. High-dose rapamycin exerts a temporary impact on T. reesei RUT-C30 through gene trFKBP12. Biotechnology for Biofuels, 2021, 14:77.  (IF: 7.7; 1区)

  24. （24）Ai-Ping Pang, Haiyan Wang, Yongsheng Luo, Zihuayuan Yang, Zhiyu Liu, Zhao Wang, Bingzhi Li, Song Yang, Zhihua Zhou, Xiaolin Lu, Fu-Gen Wu, Zuhong Lu*, Fengming Lin*. Dissecting cellular function and distribution of β-glucosidases in Trichoderma reesei. mBio, 2021, 12(3):e03671-20. (IF: 7.8; 1区)

  25. （25）Fengming Lin, Qiu-Yi Duan, and Fu-Gen Wu*. Conjugated Polymer-Based Photothermal Therapy for Killing Microorganisms. ACS Applied Polymer Materials, 2020, 2, 4331−4344 .(IF: 4.8; 2区)

  26. （26）Zihuayuan Yang, Ying Qiao, Junying Li, Fu-Gen Wu, Fengming Lin*. Novel Water-Soluble Photosensitizer from Trichoderma reesei for photodynamic inactivation of gram-positive bacteria. Langmuir, 2020, 36: 13227–13235. (IF: 4.3; 2区)

  27. （27）Liang Ma, Ai‑Ping Pang, Yongsheng Luo, Xiaolin Lu* and Fengming Lin*. Beneficial factors for biomineralization by ureolytic bacterium Sporosarcina pasteurii.Microbial Cell Factory, 2020, 19:12. (IF: 5.3; 2区)

  28. （28）Chengcheng Li, Ai-Ping Pang, Hang Yang, Rongjin Lv, Zhihua Zhou, Fu-Gen Wu, Fengming Lin*. Tracking localization and secretion of cellulase spatiotemporally and directly in living Trichoderma reesei. Biotechnology for biofuels, 2019,12, 200. (IF: 7.7; 2区)

  29. （29）Fengming Lin, Hao-Ran Jia, and Fu-Gen Wu. Glycol chitosan: A water-soluble polymer for cell imaging and drug delivery. Molecules 24.23 (2019): 4371. (IF: 4.9; 3区)

  30. （30）Fengming Lin, Yan-Wen Bao, and Fu-Gen Wu. Carbon Dots for Sensing and Killing Microorganisms. C-Journal of Carbon Research, 2019, 5: 33.

  31. （31）Chengcheng Li, Fengming Lin*, Wei Sun, Shaoxun Yuan, Zhihua Zhou, Fu‑Gen Wu and Zhan Chen. Constitutive hyperproduction of sorbicillinoids in Trichoderma reesei ZC121. Biotechnology for Biofuels, 2018, 11:291.(IF: 7.7; 1区)

  32. （32）Fengming Lin, Yan-Wen Bao and Fu-Gen Wu. Improving the Phototherapeutic Efficiencies of Molecular and Nanoscale Materials by Targeting Mitochondria. Molecules, 2018, 23, 3016. (IF: 4.9; 3区)

  33. （33）Fengming Lin*, Chengcheng Li, and Zhan Chen. Exopolysaccharide-Derived Carbon Dots for Microbial Viability Assessment. Frontiers in Microbiology. 2018, 9. 2697. (IF: 5.0; 2区)

  34. （34）Chengcheng Li, Fengming Lin*, Wei Sun, Fu-Gen Wu, Hang Yang, Roujing Lv, Ya-Xuan Zhu, Hao-Ran Jia, Chu Wang, Ge Gao, Zhan Chen. Self-assembled rose bengal-exopolysaccharide nanoparticles for improved photodynamic inactivation of bacteria by enhancing singlet oxygen generation directly in the solution. ACS Applied Materials & Interfaces, 2018, 10(19), 16715-16722 (IF: 10.4; 1区)

  35. （35）Fengming Lin*, Chengcheng Li, Zhan Chen. Bacteria-derived carbon dots inhibit biofilm formation of Escherichia coli without affecting cell growth. 2018, Frontiers in Microbiology, 2018, 9, 259. (IF: 5.0; 2区)

  36. （36）Chengcheng Li,Fengming Lin*, Le Zhou, Lei Qin, Bingzhi Li, Zhihua Zhou, Mingjie Jin, Zhan Chen. Cellulase hyper-production by Trichoderma reesei mutant SEU-7 on lactose. Biotechnology for Biofuels, 2017, 10, 228. (IF: 7.7; 1区)

  37. （37）Fengming Lin*, Chengcheng Li, Li Dong, Degang Fu, and Zhan Chen*. Imaging biofilm-encased microorganisms using carbon dots derived from L. plantarum. Nanoscale, 2017,9, 9056-9064. (IF: 8.3; 1区)

  38. （38）Chengcheng Li, Le Zhou, Hang Yang, Roujing Lv, Peilong Tian, Xu Li, Yaqin Zhang, Zhan Chen*, Fengming Lin*. Self-assembled Exopolysaccharide Nanoparticles for Bioremediation and Green Synthesis of Noble Metal Nanoparticles. ACS Applied Materials & Interfaces, 2017,9, 22808−22818. (IF: 10.4; 1区).

  39. （39）Chengcheng Li, Fengming Lin*, Yizhen Li, Wei Wei, Hongyin Wang, Lei Qin, Zhihua Zhou, Bingzhi Li, Fugen Wu, Zhan Chen, A beta-glucosidase hyper-production Trichoderma reesei mutant reveals a potential role of cel3D in cellulose production. Microbial Cell Factories，2016，15（1）：151. (IF:6.4; 2区)

  40. （40）Fengming Lin, Kyle L. Fergusion, David R. Boyer, Xiaoxia Nina Lin, E. Neil G. Marsh. Isofunctional enzymes PAD1 and UbiX catalyze formation of a novel cofactor required by Ferulic Acid Decarboxylase and 4-Hydroxy-3-polyprenylbenzoic Acid Decarboxylase. ACS Chemical Biology, 2015, 10, 1137-1144. (IF: 4.6; 2区)

  41. （41）Fengming Lin, E. Neil G. Marsh, Xiaoxia Nina Lin. Recent progress in hydrocarbon biofuel synthesis: pathways and enzymes. Chinese Chemical Letters, 2015, 26, 431-434. (IF: 8.5; 2区)

  42. （42）Fengming Lin, Yu Chen, Robert Levine, Kilho Lee, Yingjin Yuan, Xiaoxia Nina Lin. Improving fatty acid availability for bio-hydrocarbon production in Escherichia coli by metabolic engineering. PLoS One, 2013, 8(10): e78595. (IF: 3.7; 3区)

  43. （43）Fengming Lin, Debasis Das, Xiaoxia Nina Lin, E. Neil G. Marsh. Aldehyde-forming fatty acyl-CoA reductase from cyanobacteria: expression, purification and characterization of the recombinant enzyme.FEBS Journal, 2013, 280:4773-4781. (IF:5.6; 2区)   

  44. （44）Fengming Lin, Ying Tan, Ying-jin Yuan. Temperal quantitative proteomics of Saccharomyces cerevisiae in response to a nonlethal concentration of furfural. Proteomics, 2009, 9:5471-5483. (IF:5.4; 2区)

  45. （45）Fengming Lin, Bin Qiao, Ying-jin Yuan. Comparative proteomic analysis of tolerance and adaptation of ethanologenic Saccharomyces cerevisiae to furfural, a lignocellulosic inhibitory compound. Applied and Environmental Microbiology, 2009, 75(1):3765-3776. (IF:5.0; 2区)