陈怡,副研究员、博士生导师。现任生物医学工程系副主任,生物医学工程国家级实验教学示范中心副主任。中国科协“海智计划”特聘专家,全国纳米技术标准化技术委员会纳米生物医药标准化工作组委员,生物医学工程学会第十一届理事会青委会委员,中国抗癌协会纳米肿瘤学专委会青年委员,江苏省生物医学工程学会教育与科普专委会委员。获得中国科协首届“青年人才托举工程”托举人才;江苏省“双创计划”双创博士;江苏省第十二批科技镇长团“省优秀团员”、“省荣誉团员”;苏州市吴江区人才科技工作特别顾问;苏州独墅湖科教创新区科教骨干人才;“张江高科”奖教金等荣誉与称号。近年来已在Adv. Mater., Nano Lett., Adv. Func. Mater., ACS Nano, Adv. Sci., Adv. Opt. Mater., ACS Sens., Mater. Today, Biosens. Bioelectron., Chem. Eng. J.等生物纳米技术与传感器件领域国际权威期刊发表SCI收录论文30余篇,专著章节1篇。
工作经历与教育背景
· 2014.12-至今 东南大学,生物科学与医学工程学院,副研究员
· 2010.07-2014.07 蒙纳士大学(MONASH University),博士
· 2007.09-2010.03 上海交通大学,化学化工学院高分子化学与物理专业,理学硕士
· 2003.09-2007.06 华东理工大学,材料科学与工程学院高分子材料与工程专业,工学学士
研究方向与兴趣:序构增敏感测
· 微纳序构材料及其生物医学检测传感:功能微纳材料可控合成与修饰,微纳超晶格组装材料,纳米晶/聚合物复合组装材料,微纳组装柔性光电材料
· 微纳材料多尺度构效分析与可控性能:增敏传感构效分析,光电磁等可控性能设计(如表面增强拉曼散射、等离激元共振耦合与杂化、磁驱调控/刺激与成像分析等)
· 集成式柔性传感器件与生物医学应用:化学/生物标志物高效捕获检测、特异性识别、分子感应、增敏检测器件,电子皮肤/植入式交互器件,磁性微纳器件
人才称号及荣誉
1. 中国科协首届“青年人才托举工程”托举人才(No.YESS20150050)
青托人才介绍视频:https://v.douyin.com/LpvTVG8/
2. 江苏省“双创计划”双创博士
3. 江苏省委组织部第十二批科技镇长团“省优秀团员”、“省荣誉团员”
科研项目
1. 国家自然科学基金面上项目,2025/1-2028/12,主持
2. 国家自然科学基金青年基金,2016/1-2018/12,主持
3. KJ委GF科技创新特区项目-子课题,2020/12-2022/12,主持
4. 江苏省自然科学基金面上项目,2023/7-2026/6,主持
5. 苏州市基础研究计划前沿技术研究项目,2023/7-2026/6,主持
6. 苏州市重点产业技术创新前瞻性应用研究项目,2019/7-2021/6,主持
7. 苏州市应用基础研究项目,2015/7-2018/7,主持
8. 横向技装项目,***,2023/9-2024/9,主持
9. 国家重点研发计划纳米前沿重点专项(2021YFA1201400),2021/12-2026/11,参与
10. 国家自然科学基金重点项目(11734005),2018/1-2022/12,参与
11. 国家自然科学基金重点项目(92163213),2022/1-2025/12,参与
教学与人才培养
1. 本科课程:《生物材料创新与前沿》(课程思政示范课),《无机化学》,《分析化学》
2. 研究生课程:《先进材料创制与前沿》,《纳米科学技术引论》,《功能材料创制和应用(全英文-东蒙)》,《生物电子学(全英文-东蒙)》,《健康数据科学最新进展(参讲,全英文-东蒙)》
3. 主持校级本科及研究生教改项目3项
4. 2019年江苏省优秀本科毕业论文二等奖(王鲜宣);2023东大优秀硕士论文指导老师(张恒);2023东大学习优秀生“优秀导师”(杨成)
5. 全国生物医学工程创新设计竞赛三等奖(杨成等;2023&2024连续两届获奖)
代表性论文及专著(SELECTED PUBLICATIONS)
(1). Zhang, H.; Zhang, H. Q.; Sikdar, D.; Liu, X. C.; Yang, Z. R.; Cheng, W. L.; Chen, Y.*, Jellyfish-like Gold Nanowires as FlexoSERS Sensors for Sweat Analysis. Nano Letters 2024, accepted.
(2). Zhang, H.; Lin, F.; Chen, G.; Yang, C.; Zhang, H. Q.; Yan, M.; Li, H.; Wang, X.; Cheng, W. L.; Chen, Y.*, Intrinsically stretchable jellyfish-like gold nanowires film as multifunctional wearable chemical and physical sensors. Chemical Engineering Journal 2024, 490, 151798.
(3). Gao, M. M.; Zhang, D.*; Chen, Y.*; Zhang, Y.; Wang, Z.; Wang, X.; Li, S.; Guo, Y.; Webb, G. I.; Nguyen, A. T. N.; May, L.; Song, J.*, GraphormerDTI: A graph transformer-based approach for drug-target interaction prediction. Computers in Biology and Medicine 2024, 173, 108339.
(4). Zhang, H.; Lin, F. E.; Cheng, W. L.; Chen, Y.*; Gu, N.*, Hierarchically Oriented Jellyfish-like Gold Nanowires Film for Elastronics. Advanced Functional Materials, 2023, 2209760.
(5). Chen, Y.*; Bai, Y.; Wang, X.; Zhang, H.; Zheng, H.; Gu, N.*, Plasmonic/magnetic nanoarchitectures: From controllable design to biosensing and bioelectronic interfaces. Biosensors and Bioelectronics, 2023, 219, 114744.
(6). Zhang, H.; Wang, R.; Sikdar, D.; Wu, L. Y.; Sun, J.; Gu, N.; Chen, Y.*,Plasmonic Superlattice Membranes Based on Bimetallic Nano-Sea Urchins as High-Performance Label-Free Surface-Enhanced Raman Spectroscopy Platforms. ACS Sensors, 2022, 7, 2, 622-631
(7). Chen, Y.*; Yin, H.; Sikdar, D.; Yan, L.; Zhou, Z.; Sun, J.*; Wang, C., Gold Nanopolyhedron-Based Superlattice Sheets as Flexible Surface-Enhanced Raman Scattering Sensors for Detection of 4-Aminothiophenol. ACS Applied Nano Materials 2021, 4, 12498-12505.
(8). Chen, Y.; Yin, H.; Sikdar, D.; Liu, H.; Zhu, Q.; Yao, G.; Qi, H.; Gu, N.*, Multiscale Patterned Plasmonic Arrays for Highly Sensitive and Uniform SERS Detection. Advanced Materials Interfaces 2020, 7, 2000248
(9). Chen, Y.; Liu, H.; Yin, H.; Zhu, Q.; Yao, G.; Gu, N.*, Hierarchical Fabrication of Plasmonic Superlattice Membrane by Aspect-Ratio Controllable Nanobricks for Label-Free Protein Detection. Frontiers in Chemistry 2020, 8:307
(10).Chen, Y.*; Bai, Y.; Zhang, H.; Zhou, Z., Plasmonic nanoassemblies for surface-enhanced Raman scattering-based biodetection and biomedical theranostics. STEMedicine 2022, 3 (4), e147
(11).Si, K. J.; Chen, Y.; Shi, Q.; Cheng, W. L.*, Nanoparticle Superlattices: The Roles of Soft Ligands. Advanced Science 2018,5 (1), 1700179.
(12).Si, K. J.; Chen, Y.; Cheng, W. L.* Plasmene Origami. Materials Today. 2016, 19 (6), 363-364.
(13).Chen, Y.; Si, K. J.; Sikdar, D.; Tang, Y.; Premaratne, M.; Cheng, W. L.*, Ultrathin Plasmene Nanosheets as Soft and Surface-Attachable SERS Substrates with High Signal Uniformity. Advanced Optical Materials 2015, 3, 919-924.
(14).Chen, Y.; Ouyang, Z.; Gu, M.; Cheng, W. L.*, Mechanically Strong, Optically Transparent, Giant Metal Superlattice Nanomembranes From Ultrathin Gold Nanowires. Advanced Materials 2013, 25, 80-85.
(15).Chen, Y.; Cheng, W. L.*, DNA-based plasmonic nanoarchitectures: from structural design to emerging applications. Wiley Interdisciplinary Reviews - Nanomedicine and Nanobiotechnology 2012, 4, 587-604.
(16).Chen, Y.; Fu, J.; Ng, K. C.; Tang, Y.; Cheng, W. L.*, Free-Standing Polymer-Nanoparticle Superlattice Sheets Self-Assembled at the Air Liquid Interface. Crystal Growth & Design 2011, 11, 4742-4746.
(17).Chen, Y.; Ng, K. C.; Yan, W.; Tang, Y.; Cheng, W. L.*, Ultraflexible plasmonic nanocomposite aerogel. RSC Advances 2011, 1, 1265-1270.
(18).Chen, Y.; Pang, X.-H.; Dong, C.-M.*, Dual Stimuli-Responsive Supramolecular Polypeptide-Based Hydrogel and Reverse Micellar Hydrogel Mediated by HostGuest Chemistry. Advanced Functional Materials 2010, 20, 579-586.
(19).Chen, Y.; Dong, C.-M.*, pH-Sensitive Supramolecular Polypeptide -Based Micelles and Reverse Micelles Mediated by Hydrogen-Bonding Interactions or Host−Guest Chemistry: Characterization and In Vitro Controlled Drug Release. Journal of Physical Chemistry B 2010, 114, 7461-7468.
(20).Si, K. J.; Sikdar, D.;Chen, Y.; Xu, Z.; Tang, Y.; Xiong, W.; Guo, P.; Zhang, S.; Lu, Y.; Bao, Q.; Zhu, W.; Premaratne, M.; Cheng, W. L.*, Giant Plasmene Nanosheets, Nanoribbons, and Origami. ACS Nano 2014, 8, 11086-11093.
(21).Su, B.; Wu, Y.; Tang, Y.; Chen, Y.; Cheng, W. L.*; Jiang, L., Free-Standing 1D Assemblies of Plasmonic Nanoparticles. Advanced Materials 2013, 25, 3968-3972.
(22).Tang, Y.; Gong, S.; Chen, Y.; Yap, L. W.; Cheng, W. L.*, Manufacturable Conducting Rubber Ambers and Stretchable Conductors from Copper Nanowire Aerogel Monoliths. ACS Nano 2014, 8, 5707-5714.
(23).Gong, S.; Schwalb, W; Wang, Y. W.; Chen, Y.; Tang, Y.; Si, J.; Shirinzadeh, B.; Cheng, W. L.*, A wearable and highly sensitive pressure sensor with ultrathin gold nanowires. Nature Communications 2014, 5:3132.
(24).Xie, S. Y., Chen, Y., Ouyang, Z., Jia, B. H., Cheng, W. L.*, Gu, M.*, Transparent gold nano-membranes for the enhanced light trapping of the indium tin oxide films. Optical Materials Express 2014, 4, 321-328.
(25).Peng, S.-M.; Chen, Y.; Hua, C.; Dong, C.-M.*, Dendron-like Polypeptide/Linear Poly(ethylene oxide) Biohybrids with Both Asymmetrical and Symmetrical Topologies Synthesized via the Combination of Click Chemistry and Ring-Opening Polymerization. Macromolecules 2008, 42, 104-113.
(26).Yang, W. J.; Chen, Y.; Cheng, W. L., Book chapter in Handbook of Nanomaterials Properties, Springer, 3879 words, ISBN 978-3-642-31107-9, 2014.
专利
(1). 陈怡,刘晃,殷豪景,顾宁,“一种基于金银纳米砖的可控微纳阵列的构建方法及其应用”,中国发明专利(ZL201811001014.X)
(2). 陈怡,周正,严玲琳,时画,顾宁,“一种基于金属纳米粒子和微凝胶的复合药物载体及其应用”,中国发明专利(ZL201810999323.4)
(3). 陈怡,张恒,顾宁,“一种可拉伸仿生簇状金纳米线薄膜及制备方法与应用”,中国发明专利(ZL202210058000.1)
(4). 陈怡,张恒,吴临远,顾宁,“一种异质贵金属海胆型纳米晶体、其二维超晶格薄膜及其制备方法和应用”,中国发明专利, (ZL202011404247.1)
(5). 陈怡,张恒,顾宁,“基于金纳米森林结构的柔性可拉伸SERS基底及其制法和应用”,中国发明专利(2023118461938)
(6). 陈怡,张雪,顾宁,“一种基于梭型纳米晶体的SERS检测器及其制法和应用”,中国发明专利(202210479704.6)
(7). 陈怡,叶悠扬,张恒,顾宁,“金银铂核壳镂空纳米砖及其制备方法与应用”,中国发明专利,(202110290301.2)
(8). 陈怡,殷豪景,刘晃,顾宁,“一种柔性可转移型表面增强拉曼检测基底及其制备方法和应用”,中国发明专利(201811146011.5)
(9). 陈怡,刘晃,殷豪景,顾宁,“一种二维柔性贵金属纳米粒子超晶格薄膜及其构建方法和应用”,中国发明专利(201811090882.X)
本小组从属于江苏省生物材料与器件重点实验室(顾宁院士纳米组),每年招收博士生1名,学硕2名/专硕3名,欢迎同学们联系并加入课题组。
同时,欢迎报考东南大学-蒙纳士大学联合研究生院生物与医药(生物纳米技术)及电子信息(健康数据)联培专硕学位;欢迎计划出国留学深造的同学与我联系,也欢迎报考东南大学-蒙纳士大学联合研究院联合培养博士项目。
Positions for postgraduate students (Master and PhD) and Postdoc are available in our group. We are looking for highly-motivated Master/PhD candidates to join us. The positions are open for students with background in Chemistry, Chemical Engineering, Materials Engineering, Materials science or Biological Engineering, etc. Please send inquiries along with a detailed CV to Prof. Yi Chen (yichen@seu.edu.cn). Experiences in Nanomaterials, Polymer science and engineering, Self-assembled Nanomaterials, Theranostics, Surface chemistry, Nanofabrication, Biology, Bioelectronics is a plus.
通讯地址(CONTACT INFO)
东南大学九龙湖校区医工楼1201 / 丁家桥校区小蓝楼三楼
School of Biological Science and Medical Engineering
Jiangsu Key Laboratory for Biomaterials and Devices
SEU-MONASH Joint Graduate School (Suzhou)
Southeast University
C/O: Rm 1201, BME Building, Jiulonghu Campus, Nanjing | 211102
E-mail:yichen@seu.edu.cn