何春鹏 研究员
一、基本信息
陆祖宏课题组；性别：男；学历：博士；1980年5月生人；民族：汉；Tel：86-17798550441；Email: cphe@seu.edu.cn。
二、研究方向
1. 以海洋生物（文昌鱼）细胞内消化机制为基础，开发可降解（太湖）蓝藻等有害藻类及其毒素的新型混合酶制剂，以及蓝藻资源化治理利用技术系统。
2. 以造礁石珊瑚为研究对象，开展生物造礁、护礁、固礁及造礁珊瑚多组学研究。
3. 以文昌鱼、七鳃鳗和寒武纪化石样本为研究对象，探索脊椎动物机体建构模式（Body plan）的演化起源。
三、代表性文章
1. 造礁(石)珊瑚研究方向（列举10篇以内）:
1. Li, Y., Liao, X., Wang, X., Li, Y., Zhao, H., Zhao, Y., Chen, J., He, C., & Lu, Z. (2023). Polyp-Canal Reconstruction Reveals Evolution Toward Complexity in Corals. Research, 6, 0166. https://doi.org/10.34133/research.0166 [通信作者]
2. Han, T., Liao, X., Guo, Z., Chen, J. Y., He, C., & Lu, Z. (2023). Deciphering temporal gene expression dynamics in multiple coral species exposed to heat stress: Implications for predicting resilience. The Science of the total environment, 912, 169021. https://doi.org/10.1016/j.scitotenv.2023.169021 [通信作者]
3. Han, T., Liao, X., Guo, Z., Chen, J. Y., He, C., & Lu, Z. (2023). Comparative transcriptome analysis reveals deep molecular landscapes in stony coral Montipora clade. Frontiers in genetics, 14, 1297483. https://doi.org/10.3389/fgene.2023.1297483 [通信作者]
4. Zhu, Y., Liao, X., Han, T., Chen, J. Y., He, C., & Lu, Z. (2022). Utilizing an artificial intelligence system to build the digital structural proteome of reef-building corals. GigaScience, 11, giac117. https://doi.org/10.1093/gigascience/giac117 [通信作者]
5. Zhu, Y., Liao, X., Han, T., Chen, J. Y., He, C., & Lu, Z. (2022). Symbiodiniaceae microRNAs and their targeting sites in coral holobionts: A transcriptomics-based exploration. Genomics, 114(4), 110404. https://doi.org/10.1016/j.ygeno.2022.110404 [通信作者]
6. Guo, Z., Liao, X., Chen, J. Y., He, C., & Lu, Z. (2022). Binding Pattern Reconstructions of FGF-FGFR Budding-Inducing Signaling in Reef-Building Corals. Frontiers in physiology, 12, 759370. https://doi.org/10.3389/fphys.2021.759370 [通信作者]
7. Han, T., Liao, X., Zhu, Y., Liu, Y., Lu, N., Li, Y., Guo, Z., Chen, J. Y., He, C., & Lu, Z. (2022). Full-Length Transcriptome Maps of Reef-Building Coral Illuminate the Molecular Basis of Calcification, Symbiosis, and Circadian Genes. International journal of molecular sciences, 23(19), 11135. https://doi.org/10.3390/ijms231911135 [通信作者]
8. Liu, Y., Zhu, Y., He, C., & Lu, Z. (2021). BENviewer: a gene interaction network visualization server based on graph embedding model. Database: the journal of biological databases and curation, 2021, baab033. https://doi.org/10.1093/database/baab033 [通信作者]
9. Li, Y., Liao, X., Bi, K., Han, T., Chen, J., Lu, J., He, C., & Lu, Z. (2021). Micro-CT reconstruction reveals the colony pattern regulations of four dominant reef-building corals. Ecology and evolution, 11(22), 16266–16279. https://doi.org/10.1002/ece3.8308 [通信作者]
10. Li, Y., Han, T., Bi, K., Liang, K., Chen, J., Lu, J., He, C., & Lu, Z. (2020). The 3D Reconstruction of Pocillopora Colony Sheds Light on the Growth Pattern of This Reef-Building Coral. iScience, 23(6), 101069. https://doi.org/10.1016/j.isci.2020.101069 [通信作者]
2. 海洋生物（文昌鱼）细胞内消化机制研究方向（列举5篇以内）:
1. He, C., Han, T., Liao, X., Zhou, Y., Wang, X., Guan, R., Tian, T., Li, Y., Bi, C., Lu, N., He, Z., Hu, B., Zhou, Q., Hu, Y., Lu, Z., & Chen, J. Y. (2018). Phagocytic intracellular digestion in amphioxus (Branchiostoma). Proceedings. Biological sciences, 285(1880), 20180438. https://doi.org/10.1098/rspb.2018.0438 [第一作者；《自然》杂志专题评述: The sea creature that swallows its food whole - twice. (2018). Nature, 558(7709), 165. https://doi.org/10.1038/d41586-018-05396-3]
2. He, C., Han, T., Liao, X., Guan, R., Chen, J. Y., Tremblay, K. D., & Lu, Z. (2020). On the origin of vertebrate body plan: Insights from the endoderm using the hourglass model. Gene expression patterns, 37, 119125. https://doi.org/10.1016/j.gep.2020.119125 [第一作者；封面文章]
3. Bi, C., Lu, N., Huang, Z., Chen, J., He, C., & Lu, Z. (2020). Whole-genome resequencing reveals the pleistocene temporal dynamics of Branchiostoma belcheri and Branchiostoma floridae populations. Ecology and evolution, 10(15), 8210–8224. https://doi.org/10.1002/ece3.6527 [通信作者]
4. Bi, C., Lu, N., Xu, Y., He, C., & Lu, Z. (2020). Characterization and Analysis of the Mitochondrial Genome of Common Bean (Phaseolus vulgaris) by Comparative Genomic Approaches. International journal of molecular sciences, 21(11), 3778. https://doi.org/10.3390/ijms21113778 [通信作者]
5. Zhu, Y., Lu, N., Chen, J. Y., He, C., Huang, Z., & Lu, Z. (2022). Deep whole-genome resequencing sheds light on the distribution and effect of amphioxus SNPs. BMC genomic data, 23(1), 26. https://doi.org/10.1186/s12863-022-01038-w [通信作者]
四、造礁石珊瑚NCBI标准参考基因组（NCBI RefSeq）组装
https://www.ncbi.nlm.nih.gov/datasets/genome/?taxon=6125
1. Acropora muricata
https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_036669905.1/
2. Montipora capricornis
https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_036669925.1/
3. Montipora foliosa
https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_036669935.1/
4. Pocillopora verrucosa
https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_036669915.1/
五、教学成果
Algae Terminator: Earth intelligence against earth cancer. 获得2019 iGEM国际遗传工程机器设计竞赛金奖，https://2019.igem.org/Team:SEU-Nanjing-China/
六、获奖情况
第八届国际海洋科学家奖 (排名第一；国际海洋科学家协会; 突破性创新奖, 2024年；https://marinescientist.org/)