何泓良,东南大学青年首席教授,博士生导师,国家级青年人才。现任东南大学生物科学与医学工程学院副院长。主要从事纳米药物设计工作,长期致力于利用纳米技术围绕血管疾病(如动脉粥样硬化、血栓等)构建精准治疗新技术和新方法。主持承担国家高层次青年人才项目,国家自然科学基金面上项目、青年项目,南京市留学人员科技创新项目等项目,参与国家重点研发计划。以第一或通讯作者在 Science Advances, ACS Nano, Advanced Science, Biomaterials, Nano Letters, Journal of Controlled Release等期刊上发表论文40余篇,申请发明专利3项。曾获美国心脏协会博士后研究基金资助,获美国心脏协会Young Investigator Travel Award。现任Nano Research, Nano Materials Science, Asian Journal of Pharmaceutical Sciences, National Science Open等期刊青年编委。
(欢迎优秀本科生、硕士/博士研究生、博士后加入,专业背景包括但不限于生物医学工程,药学、高分子材料、化学等,联系方式:drhe518@seu.edu.cn)!
近5年代表性论文:
1 Shi Wang, H He*, Y Mao, Y Zhang*, N Gu*. Advances in Atherosclerosis Theranostics Harnessing Iron Oxide-Based Nanoparticles. Advanced Science 2024 May;11(17):e2308298.
2 H He, Q Han, S Wang, M Long, M Zhang, Y Li, Y Zhang*, N Gu*. Design of a Multifunctional Nanozyme for Resolving the Proinflammatory Plaque Microenvironment and Attenuating Atherosclerosis. ACS Nano 2023, 8;17(15):14555-14571. (Suppl. Cover)
3. D Liu, H He, (Equal Contribution) F Kong, Y Cao, F Zang, M Ma*, N Gu*, Y Zhang*, A versatile metal–organic nanoplatform in combination with CXCR4 antagonist and PD-L1 inhibitor for multimodal synergistic cancer therapy and MRI-guided tumor imaging, Nano Today 2022, 47, 101689
4. H He, TA Halseth (Equal Contribution), L Mei, C Shen, L Liu*, A Schwendeman*. Nanodisc delivery of liver X receptor agonist for the treatment of diabetic nephropathy. Journal of Controlled Release 2022, 348, 1016-1027.
5. H He, R Adili (Equal Contribution), L Liu (Equal Contribution), K Hong, M Holinstat, A Schwendeman*. Synthetic high-density lipoproteins loaded with antiplatelet agent for efficiently inhibiting thrombosis in mice. Science Advances 2020 Dec 4;6(49): eabd0130.
6. H He, J Wang, P Yannie, WJ Korzun, H Yang*, S Ghosh*. Nanoparticle-based “Two-pronged” approach to regress atherosclerosis by simultaneous modulation of cholesterol influx and efflux. Biomaterials 2020:120333.