林凤鸣

发布者:张怡茹发布时间:2020-09-04浏览次数:3816




林凤鸣,东南大学生命科学与医学工程院副研究员,博士生导师。

主要从事合成生物、系统生物学、生物医用材料等领域的研究。至今在Small StructuresACS Applied Materials & InterfacesmBioNanoscaleBiotechnology for BiofuelACS Chemical Biology等杂志发表SCI论文40篇,其中通讯/一作30篇,发表文章总引用次数1170多次。授权专利7项。主持国家自然科学青年基金和面上项目基金。参与973863等重大科技项目多项。目前的主要研究方向有1)微生物转录水平调控机理研究;(2)真菌非经典分泌途径的研究;(3)碳点的合成和应用;(4)抗菌抗癌纳米药物研发。


 工作教育经历

2014/9-至今,  东南大学,      生医学院,    副教授

2011/9-2014/8, 美国密歇根大学,化工系和化学系,博士后

2005/9-2011/6,天津大学,  制药工程,   博士,元英进 。  

2009/9-2011/6,美国密歇根大学, 化学工程系, 联合培养 Xiaoxia Nina Lin

2001/9-2005/9,天津大学, 制药工程,   学士。


已发表的论文:

(1)    Fengming Lin, Cheyang Jia, Fu-Gen Wu*,Carbon dots for intracellular sensing. Small Structures, 2022DOI: 10.1002/sstr.202200033. (IF: 11.3)

(2)    Ai-Ping Pang, Yongsheng Luo, Xin Hu, Funing Zhang, Haiyan Wang,a Yichen Gao, Samran Durrani, Chengcheng Li, Xiaotong Shi, Fu-Gen Wu, Bing-Zhi Li, Zuhong Lu*, Fengming Lin*. Transmembrane transport process and endoplasmic reticulum function facilitate the role of gene cel1b in cellulase production of Trichoderma reesei. Microbial Cell Factories, 2022. (IF: 6.4; 2)

(3)    Yichen Gao, Ai-Ping Pang, Leyao Ma, Haiyan Wang, Samran Durrani, Bingzhi Li, Fu-Gen Wu, Fengming Lin*. Intron retention coupled with nonsense-mediated decay is involved in cellulase biosynthesis in cellulolytic fungi. Biotechnology for Biofuels, 2022.  (IF:7.7; 1)

(4)    Samran Durrani, Jie Zhang, Ai-Ping Pang, Yichen Gao, Tian-Yu Wang, Haiyan Wang, Fu-Gen Wu, Fengming Lin*. Carbon dots for multicolor cell imaging and ultra-sensitive detection of multiple ions in living cells: one stone for multiple birds. Environmental Research, 2022,212:1113260 (IF: 8.4; 2)

(5)    Samran Durrani, Jie Zhang , Zihuayuan Yang, Ai-Ping Pang, Jia Zeng, Sayed Mir Sayed, Adeel Khan, Yaqin Zhang, Fu-Gen Wu, Fengming Lin *. Plant-derived Ca, N, S-Doped carbon dots for fast universal cell imaging and intracellular Congo red detection. Analytica Chimica Acta, 2022, 339672. (IF: 6.9; 1)

(6)    Jie Zhang, Zihuayuan Yang, Yan-Hong Li, Samran Durrani, Ai-Ping Pang, Yichen Gao, Fu-Gen Wu, Fengming Lin*. Super stable chitosan-based nanoparticles for broad-spectrum antimicrobial photodynamic therapy.ACS Applied Polymer Materials, 2022, 4:425–434. (IF: 4.8; 2)

(7)    Ai-Ping Pang, Funing Zhang, Xin Hu, Yongsheng Luo, Haiyan Wang, Samran Durrani, Fu-Gen Wu, Bing-Zhi Li, Zhihua Zhou, Zuhong Lu*, Fengming Lin*. Glutamine involvement in nitrogen regulation of cellulase production in fungi. Biotechnology for Biofuels, 2021, 14:199.  (IF: 7.7; 1)

(8)    Ai-Ping Pang, Haiyan Wang, Funing Zhang, Xin Hu, Fu-Gen Wu, Zhihua Zhou, Wei Wang, Zuhong Lu*, Fengming Lin*. High-dose rapamycin exerts a temporary impact on T. reesei RUT-C30 through gene trFKBP12. Biotechnology for Biofuels, 2021, 14:77.  (IF: 7.7; 1)

(9)    Ai-Ping Pang, Haiyan Wang, Yongsheng Luo, Zihuayuan Yang, Zhiyu Liu, Zhao Wang, Bingzhi Li, Song Yang, Zhihua Zhou, Xiaolin Lu, Fu-Gen Wu, Zuhong Lu*, Fengming Lin*. Dissecting cellular function and distribution of β-glucosidases in Trichoderma reesei. mBio, 2021, 12(3):e03671-20. (IF: 7.8; 1)

(10)Fengming Lin, Qiu-Yi Duan, and Fu-Gen Wu*. Conjugated Polymer-Based Photothermal Therapy for Killing Microorganisms. ACS Applied Polymer Materials, 2020, 2, 4331−4344 .(IF: 4.8; 2)

(11)Zihuayuan Yang, Ying Qiao, Junying Li, Fu-Gen Wu, Fengming Lin*. Novel Water-Soluble Photosensitizer from Trichoderma reesei for photodynamic inactivation of gram-positive bacteria. Langmuir 2020, 36, 44, 13227–13235. (IF: 4.3; 2)

(12)Liang Ma, Ai‑Ping Pang, Yongsheng Luo, Xiaolin Lu* and Fengming Lin*. Beneficial factors for biomineralization by ureolytic bacterium Sporosarcina pasteurii.Microbial Cell Factory, 2020, 19:12. (IF: 5.3; 2)

(13)Chengcheng Li, Ai-Ping Pang, Hang Yang, Rongjin Lv, Zhihua Zhou, Fu-Gen Wu, Fengming Lin*. Tracking localization and secretion of cellulase spatiotemporally and directly in living Trichoderma reesei. Biotechnology for biofuels, 2019,12, 200. (IF: 7.7; 2)

(14)Fengming Lin, Hao-Ran Jia, and Fu-Gen Wu. Glycol chitosan: A water-soluble polymer for cell imaging and drug delivery. Molecules 24.23 (2019): 4371. (IF: 4.9; 3)

(15)Fengming Lin, Yan-Wen Bao, and Fu-Gen Wu. Carbon Dots for Sensing and Killing Microorganisms. C-Journal of Carbon Research, 2019, 5: 33.

(16)Chengcheng Li, Fengming Lin*, Wei Sun, Shaoxun Yuan, Zhihua Zhou, FuGen Wu and Zhan Chen. Constitutive hyperproduction of sorbicillinoids in Trichoderma reesei ZC121. Biotechnology for Biofuels, 2018, 11:291.(IF: 7.7; 1)

(17)Fengming Lin, Yan-Wen Bao and Fu-Gen Wu. Improving the Phototherapeutic Efficiencies of Molecular and Nanoscale Materials by Targeting Mitochondria. Molecules, 2018, 23, 3016. (IF: 4.9; 3)

(18)Fengming Lin*, Chengcheng Li, and Zhan Chen. Exopolysaccharide-Derived Carbon Dots for Microbial Viability Assessment. Frontiers in Microbiology. 2018, 9. 2697. (IF: 5.0; 2)

(19)Chengcheng Li, Fengming Lin*, Wei Sun, Fu-Gen Wu, Hang Yang, Roujing Lv, Ya-Xuan Zhu, Hao-Ran Jia, Chu Wang, Ge Gao, and   Zhan Chen. Self-assembled rose bengal-exopolysaccharide nanoparticles for improved photodynamic inactivation of bacteria by enhancing singlet oxygen generation directly in the solution. ACS Applied Materials & Interfaces, 2018, 10(19), 16715-16722 (IF: 10.4; 1)

(20)Fengming Lin*, Chengcheng Li, Zhan Chen. Bacteria-derived carbon dots inhibit biofilm formation of Escherichia coli without affecting cell growth. 2018, Frontiers in Microbiology, 2018, 9, 259. (IF: 5.0; 2)

(21)Chengcheng Li,Fengming Lin*, Le Zhou, Lei Qin, Bingzhi Li, Zhihua Zhou, Mingjie Jin, Zhan Chen. Cellulase hyper-production by Trichoderma reesei mutant SEU-7 on lactose. Biotechnology for Biofuels, 2017, 10, 228. (IF: 7.7; 1)

(22)Fengming Lin*, Chengcheng Li, Li Dong, Degang Fu, and Zhan Chen*. Imaging biofilm-encased microorganisms using carbon dots derived from L. plantarum. Nanoscale, 2017,9, 9056-9064. (IF: 8.3; 1)

(23)Chengcheng Li, Le Zhou, Hang Yang, Roujing Lv, Peilong Tian, Xu Li, Yaqin Zhang, Zhan Chen*, Fengming Lin*. Self-assembled Exopolysaccharide Nanoparticles for Bioremediation and Green Synthesis of Noble Metal Nanoparticles. ACS Applied Materials & Interfaces, 2017,9, 22808−22818. (IF: 10.4; 1).

(24)Chengcheng Li, Fengming Lin*, Yizhen Li, Wei Wei, Hongyin Wang, Lei Qin, Zhihua Zhou, Bingzhi Li, Fugen Wu, Zhan Chen, A beta-glucosidase hyper-production Trichoderma reesei mutant reveals a potential role of cel3D in cellulose production. Microbial Cell Factories2016151):151. (IF:6.4; 2)

(25)Fengming Lin, Kyle L. Fergusion, David R. Boyer, Xiaoxia Nina Lin, E. Neil G. Marsh. Isofunctional enzymes PAD1 and UbiX catalyze formation of a novel cofactor required by Ferulic Acid Decarboxylase and 4-Hydroxy-3-polyprenylbenzoic Acid Decarboxylase. ACS Chemical Biology, 2015, 10, 1137-1144. (IF: 4.6; 2)

(26)Fengming Lin, E. Neil G. Marsh, Xiaoxia Nina Lin. Recent progress in hydrocarbon biofuel synthesis: pathways and enzymes. Chinese Chemical Letters, 2015, 26, 431-434. (IF: 8.5; 2)

(27)Fengming Lin, Yu Chen, Robert Levine, Kilho Lee, Yingjin Yuan, Xiaoxia Nina Lin. Improving fatty acid availability for bio-hydrocarbon production in Escherichia coli by metabolic engineering. PLoS One, 2013, 8(10): e78595. (IF: 3.7; 3)

(28)Fengming Lin, Debasis Das, Xiaoxia Nina Lin, E. Neil G. Marsh. Aldehyde-forming fatty acyl-CoA reductase from cyanobacteria: expression, purification and characterization of the recombinant enzyme.FEBS Journal, 2013, 280:4773-4781. (IF:5.6; 2)   

(29)Fengming Lin, Ying Tan, Ying-jin Yuan. Temperal quantitative proteomics of Saccharomyces cerevisiae in response to a nonlethal concentration of furfural. Proteomics, 2009, 9:5471-5483. (IF:5.4; 2)

(30)Fengming Lin, Bin Qiao, Ying-jin Yuan. Comparative proteomic analysis of tolerance and adaptation of ethanologenic Saccharomyces cerevisiae to furfural, a lignocellulosic inhibitory compound. Applied and Environmental Microbiology, 2009, 75(1):3765-3776. (IF:5.0; 2)


招生信息:每年拟招收博士后,博士生1名,硕士生3名,本科毕业设计3名。希望生物医学工程、医学、生物、材料等专业的学生踊跃报考。联系方式:linfengming@seu.edu.cn