Ning-Ping Huang

发布者:孙翌发布时间:2014-12-05浏览次数:1992

Name: Ning-Ping Huang

Present Position: Professor at Southeast University, School of Biological Science and Medical Engineering, State Key Laboratory of Bioelectronics. PhD supervisor, major in Biomedical Engineering

Mail address:

School of Biological Science and Medical Engineering

Southeast University

Nanjing, 210096

P.R.China

Tel: 0086-25-83790820-802

E-mail:nphuang@seu.edu.cn

  

Education:

1994-1997: Southeast University, M.E. in Biomedical Engineering, March 1997

1998-2002: Swiss Federal Institute of Technology (ETH) Zurich, Ph.D. in Material Science, April 2002

Work experiences:

2002.4-2005.9: Postdoctoral Fellow, Institute for Structural Biology, Biozentrum,

University of Basel, Switzerland

2005.10-present: State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University. Professor (since 2012)

  

Research Interests:

  1. Organs-on-chips, in particular on construction of heart-on-a-chip (organoid) based on iPSC-derived cardiomyocytes for drug testing and disease modeling;

  2. Effect of surface nanotopography or nanostructured materials on stem cell behavior (adhesion, proliferation and differentiation) and the underlying mechanism;

  3. Biomaterials (nanofibers, hydrogels) and tissue engineering (nerve tissue engineering, cardiac tissue engineering);

  4. Controlled drug delivery system for targeting cardiovascular diseases (e.g. atheromatous plaque by functionalized polymeric nanoparticles).

      

    Selected publications:

  5. Feng Zhang, Ning Zhang, Hong-Xu Meng, Hai-Xia Liu, Ying-Qi Lu, Chao-Ming Liu, Zhao-Ming Zhang, Kai-Yun Qu, Ning-Ping Huang*, Easy Applied Gelatin-Based Hydrogel System for Long-Term Functional Cardiomyocyte Culture and Myocardium Formation, ACS Biomaterials Science and Engineering, DOI: 10.1021/acsbiomaterials.9b00515, 2019

  6. Ning Zhang, Flurin Stauffer, Benjamin R. Simona, Feng Zhang, Zhao-Ming Zhang, Ning-Ping Huang*, János Vörös*, Multifunctional 3D electrode platform for real-time in situ monitoring and stimulation of cardiac tissues, Biosensors and Bioelectronics 112:149–155, 2018

  7. Kai-Hong Wu*, Qian-Ru Xiao, Yu Yang, Jia-Li Xu, Feng Zhang, Chao-Ming Liu, Zhao-Ming Zhang, Ying-Qi Lu, Ning-Ping Huang*, MicroRNA-34a modulates the Notch signaling pathway in mice with congenital heart disease and its role in heart development. Journal of Molecular and Cellular Cardiology 114: 300–308, 2018

  8. Xiao-Feng Zhang, Hai-Xia Liu, Lazarus Santiago Ortiz, Zhong-Dang Xiao, Ning-Ping Huang*Laminin-modified and aligned PHBV/PEO nanofibrous nerve conduits promote peripheral nerve regenerationJournal of Tissue Engineering and Regenerative Medicine12: e627-e636, 2018

  9. Ning Zhang, Vincent Milleret, Greta Thompson-Steckel, Ning-Ping Huang, Janos Vörös, Benjamin R. Simona, and Martin Ehrbar, Soft Hydrogels Featuring In-Depth Surface Density Gradients for the Simple Establishment of 3D Tissue Models for Screening Applications, SLAS discovery22(5):635-644, 2017

  10. Qian-Ru Xiao, Ning Zhang, Xi Wang, Xin-Yao Man, Ke Yang, Lan-Xin Lü and Ning-Ping Huang*Oriented Surface Nanotopography Promotes the Osteogenesis of Mesenchymal Stem CellsAdvanced Materials Interfaces, 4(3):1600652(9pp), 2017.

  11. Lan-Xin Lü, Ning-Ping Huang*, Ying Yang*Accelerating and increasing nano-scaled pore formation on electrospun Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) fibersJournal of Biomaterials Science, Polymer Edition, 27(11): 1155-1169, 2016

  12. Ning Zhang, Qian-Ru Xiao, Xin-Yao Man, Hai-Xia Liu, Lan-Xin LüNing-Ping Huang*, Spontaneous osteogenic differentiation of mesenchymal stem cells on electrospun nanofibrous scaffolds. RSC Advances 6: 22144–22152, 2016.

  13. Lan-Xin Lü, Xiao-Feng Zhang, Yan-Yan Wang, Lazarus Ortiz, Xi Mao, Zan-Li Jiang, Zhongdang Xiao, Ning-Ping Huang*, Effects of hydroxyapatite-containing composite nanofibers on osteogenesis of mesenchymal stem cells in vitro and bone regeneration in vivo, ACS Applied Materials & Interfaces, 5 (2): 319–330, 2013.

  14. Lan-Xin Lü, Yan-Yan Wang, Xi Mao, Zhong-Dang Xiao, Ning-Ping Huang*, The effects of PHBV electrospun fibers with different diameters and orientations on growth behavior of bone marrow-derived mesenchymal stem cells. Biomedical Materials 7(1): 015002 (10pp), 2012.

  15. Ning-Ping Huang*, Susan De Paul, Marcus Textor, “Docking Sites”: Nanometer-scale Organization of a Reactive, Protein-resistant, Graft Copolymer-based Interface for Macromolecule Immobilization, Biomacromolecules12(12): 4213-4220 2011.

  16. Ning-Ping Huang*, Hai Yu, Yan-Yan Wang, Jun-Cai Shi, Xi MaoEfficient creation of cellular micropatterns with long-term stability and their geometric effects on cell behaviorBiointerphases, 6(4):143-152, 2011.

  17. Yan-Yan Wang, Lan-Xin Lü, Jun-Cai Shi, Hai-Feng Wang, Zhong-Dang Xiao, Ning-Ping Huang* Introducing RGD peptides on PHBV films through PEG-containing crosslinkers to improve the biocompatibility, Biomacromolecules12(3):551-559, 2011.

  18. Yan-Yan Wang, Lan-Xin Lü, Zhang-Qi Feng, Zhong-Dang Xiao, Ning-Ping Huang*Cellular Compatibility of RGD-Modified Chitosan Nanofibers with Aligned or Random OrientationBiomedical Materials 5(5):054112 (9pp), 2010.

  19. Zhang-Qi Feng, Xue-Hui Chu, Ning-Ping Huang, Michelle K. Leach, Gan Wang, Yi-Chun Wang, Yi-Tao Ding, Zhong-Ze Gu. Rat hepatocyte aggregate formation on discrete aligned nanofibers of type-I collagen-coated poly(L-lactic acid). Biomaterials 31: 3604-36122010.

  20. Zhang-Qi Feng, Hui-Jun Lu, Michelle K. Leach, Ning-Ping Huang, Yi-Chun Wang, Chang-Jian Liu, Zhong-Ze Gu. The influence of type-I collagen-coated PLLA aligned nanofibers on growth of blood outgrowth endothelial cells. Biomedical Materials 5: 065011 (8pp), 2010.

  21. Zhang-Qi Feng, Xue-Hui Chu, Ning-Ping Huang, Tao Wang, Yi-Chun Wang, Xiao-Lei Shi, Yi-Tao Ding, Zhong-Ze Gu, The effect of nanofibrous galactosylated chitosan scaffolds on the formation of rat primary hepatocyte aggregates and the maintenance of liver function, Biomaterials, 30(14)2753-27632009

  22. Ning-Ping Huang, Janos Voros, Susan M. De Paul, Marcus Textor, Nicholas D. Spencer. Biotin-derivatized Poly(L-lysine)-g-Poly(ethylene glycol): A novel polymeric interface for bioaffinity sensing. Langmuir 18: 220-230, 2002.

  23. Ning-Ping Huang, Gabor Csucs, Kazunori EmotoYukio Nagasaki, Kazunori Kataoka, Marcus Textor, Nicholas D. Spencer, Covalent attachment of novel Poly(ethylene glycol)-Poly(DL-lactic acid) copolymeric micelles to TiO2 surfaces, Langmuir, 18: 252-258, 2002

  24. Ning-Ping Huang, Roger Michel, Janos Voros, Marcus Textor, Rolf Hofer, Antonella Rossi, Donald L. Elbert, Jeffrey A. Hubbell, Nicholas D. Spencer. Poly(L-lysine)-g-poly(ethylene glycol) layers on metal oxide surfaces: Surface-analytical characterization and resistance to serum and fibrinogen adsorption. Langmuir 17: 489-498, 2001.