The researches in our group mainly focus on:

1, Nanochemistry. We actively explore new methodologies (reactions) for synthesizing nanomaterials, including dendrimers, supermolecular hydrogels, and inorganic nanoparticles for bioengineering applications.

2, Molecular and Cellular Imaging. We develop novel molecular probes for imaging or manipulating targeted biomolecules in normal and diseased states, usually for cancer early detection.

3, Imaging Modality. We combine different imaging modalities for disease diagnosis, therapy evaluation, et al.

Our lab welcomes students/scholars with diverse backgrounds and expertise including synthetic and analytical chemistry, protein and nanoparticle engineering, molecular and cellular biology, medical imaging, and many more. Each individual plays crucial roles in multiple research projects and learns knowledge from each other in the interdisciplinary projects as well. We provide an excellent research and training environment for Ph.D. scientists and graduate students, medical students and residents.

October 22, Congratulations! Lingling Xu's paper titled "Granzyme B Turns Nanoparticle Fluorescence “On” for Imaging Cytotoxic T Lymphocyte Activity in Vivo." was accepted by ACS Nano 2022. Congratulations to Lingling! DOI: 10.1021/acsnano.2c08896	Honor: 2022东南大学博士研究生国家奖学金——程晓彤 2022东南大学吴健雄纪念基金女学人计划(10W)——程晓彤 2022东南大学博士新生奖学金——蒋翘楚 2022东南大学硕士研究生国家奖学金——胡心怡 2022人工智能与数字健康全国博士后青年科技人才扬子江论坛一等奖——蒋翘楚 2022江苏省科研与实践创新计划项目——刘筱阳 2021东南大学博士新生奖学金——刘筱阳 2021东南大学硕士研究生国家奖学金——蒋翘楚 2020东南大学博士研究生新生奖学金——高歌
October 3, Congratulations! Yaguang Wang's paper titled "MMP 9-instructed assembly of bFGF nanofibers in ischemic myocardium to promote heart repair." was accepted by Theranostics 2022. Congratulations to Yaguang! DOI: 10.7150/thno.77345
September 21, Congratulations! Xiaotong Cheng's paper titled "Enzymatic Nanosphere-to-Nanofiber Transition and Autophagy Inducer Release Promote Tumor Chemotherapy." was accepted by Adv. Healthcare Mater. 2022. Congratulations to Xiaotong! DOI: 10.1002/adhm.202201916	September 3, Congratulations! Tiantian Xia and Xiaotong Cheng's paper titled "Photoswitchable Nanofiber–Nanoparticle Transformation in a Cosolvent Gel–Sol System." was accepted by ACS Materials Lett. 2022, 4, 10, 1962–1966. Congratulations to Tiantian and Xiaotong! News website: https://bme.seu.edu.cn/2022/0916/c478a420176/page.htm DOI: 10.1021/acsmaterialslett.2c00670
August 6, Congratulations! Ge Gao's paper titled "FAP-α-Instructed Coumarin Excimer Formation for High Contrast Fluorescence Imaging of Tumor." was accepted by Nano Lett. 2022, 22, 16, 6782–6786. Congratulations to Ge! News website: https://bme.seu.edu.cn/2022/0810/c478a416433/page.htm DOI: 10.1021/acs.nanolett.2c02540	June 9, Congratulations! Ge Gao's paper titled "A Trident Molecule with Nanobrush-Nanoparticle-Nanofiber Transition Property Spatially Suppresses Tumor Metastasis." was accepted by J. Am. Chem. Soc. 2022, 144, 26, 11897-11910. Congratulations to Ge! News website: https://bme.seu.edu.cn/2022/0623/c478a412544/page.htm DOI: 10.1021/jacs.2c05743