Hongde Liu


Hongde Liu, Ph.D, associate professor;

Research area: Bioinformatics, with more than 40 peer-reviewed papers as a major contributor.

Education and work experience

Received a PhD in Northwest Normal UniversityA Postdoc in Southeast University from 2006 to 2008; Work experience as a visiting scholar in Hong Kong Baptist University, Baylor College of Medicine and Emory University.

Research area

Bioinformatics: epigenomics, cancer omics. Through modeling the biomedical big data, we identified new diagnostic markers and therapeutic targets for Alzheimer’s disease and cancers.


    1. Liu H.D., Luo K., Luo D. H., (2018). Guanosine monophosphate reductase 1 is a potential therapeutic target for Alzheimer’s disease, Scientific reports 8:2759.

    2.  Liu L.J., Xie J.M., Luo K., Sun X., Qin Steve Z.H., Liu H.D.* (2017). An approach of identifying differential nucleosome regions in multiple samples. BMC Genomics, 18:135.

    3. Liu H.D., Luo K., Zhou Z.K., Mu Y., Wan Y.K. (2014). Histone chaperone Chz1 facilitates the disfavoring property of Spt16 to H2A.Z-containing genes in Saccharomyces cerevisiae. Biochem. J. 460, 387-397.

    4. Liu H.D., Duan X.Y., Yu S.X., Sun X. (2011). Analysis of nucleosome positioning determined by DNA helix curvature in the human genome. BMC Genomics. 12:72.

    5. Liu H.D., Wu J.S., Xie J.M., Yang X.N., Lu Z.H., Sun X. (2008). Characteristics of nucleosome core DNA and their applications in predicting nucleosome positions, Biophys. J. 94(12), 4597-4604.



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