黄炎

发布者:张怡茹发布时间:2013-01-23浏览次数:13364

  

黄炎、女、19778月生,江苏启东人,副研究员,中国生物医学过程学会类器官与器官芯片分会委员、干事,中国生物材料学会会员。在国内外学术期刊和国际国内会议上发表论文篇90多篇,获江苏省自然科学奖二等奖(排名第二)、中华医学科技奖二等奖各1项。Emailhylucky@seu.edu.cn025-83793430-603

教育背景:

    19996月获东南大学生物医学工程系学士学位

    20026月获东南大学生物医学工程系硕士学位

    20153月获东南大学生物医学工程学院博士学位

 研究方向:生物材料生物相容性、纳米毒理学、脑类器官、生物组学

 

主持项目:

[1]国家自然科学基金面上项目(2024/01-2027/12):基于人脑类器官的纳米银致人脑组织毒性机理研究,在研,主持

[2]国家自然科学基金青年项目(2017/01-2019/12):基于代谢组学的金、银纳米粒子细胞毒性分子机理研究,已结题,主持

[3]江苏省自然科学基金青年项目(2015/07-2018/6):不同粒径纳米银诱导的细胞毒性中关键microRNA的筛选及其作用机制研究,已结题,主持

代表性论文:

[1]     Zequn Zhang, Chen Meng, Zhigong Wang*, Yan Huang*, Xiaoying Lü*. The Effect of Silver Nanoparticles on the Electrical Activity of PC12 Quasi-Neuronal Networks and the Comparison of Two Microelectrode Array-Based Neural Signal Analysis Methods. Journal of Biomedical Nanotechnology, 2024, 20(3): 570-579SCI

[2]     Zhu Geng, Zhan Yuanbao, Lu Yu, Zheng Fei, Wan Yu, Liu B, Yang Xi, Wan Yanhui, Sun Qingjiang, Sha Jingjie, Huang Yan*, Zhao Xiangwei*. A nanostructured lateral flow immunoassay strip combined with Au@SiO2 SERS nanotags for multiplex biomarker detection. Materials Advances, 2023, 4(23):6333-6341.SCI

[3]     Chen Yao-Zhong#, Huang Yan#, Lü Xiao-Ying. Molecular mechanism of a novel root-end filling material containing zirconium oxide on the osteogenic/odontogenic differentiation of human osteosarcoma MG-63 cells. Frontiers in Bioengineering and Biotechnology, 2023, 11: 1269246.SCI

[4]     Yan Huang, Rong Chen, Shuci Yang, Ye Chen, Xiaoying Lü. The Mechanism of Interaction Between Gold Nanoparticles and Human Dermal Fibroblasts Based on Integrative Analysis of Transcriptomics and Metabolomics Data. Journal of Biomedical Nanotechnology, 2022, 18(6):1562-1576.SCI

[5]     Fudan Zhang#, Yan Huang#, Yajing Zhang, Xiaoying Lü*. Screening and validation of nickel ion cytotoxicity biomarkers based on transcriptomic and proteomic technology. Regenerative Biomaterials, 2022, 9: rbac073.SCI

[6]     Yajing Zhang#, Yan Huang#, Rong Chen, Shulin Chen, Xiaoying Lü*. The interaction mechanism of nickel ions with L929 cells based on integrative analysis of proteomics and metabolomics data. Regenerative Biomaterials, 2022, 9: rbac040.SCI

[7]     Zequn Zhang, Chen Meng, Kun Hou, Zhigong Wang*, Yan Huang*, Xiao-Ying Lü*. The cytological and electrophysiological effects of silver nanoparticles on neuron‑like PC12 cells, PLoS One, 2022, 17 (12):e027794.SCI

[8]     Chang Ning, He Jiahui, Guo Yunxia, Huang Yan*, Zhao Xiangwei*. Effects of matrigel on growth and development of cerebral organoids. Materials Express, 2022, 12(4):616-627.SCI

[9]     Xiaoman Su#, Yan Huang#, Rong Chen, Yiwen Zhang, Meichen He, Xiaoying Lü. Metabolomics analysis of poly(L-lactic acid) nanofibers’ performance on PC12 cell differentiation. Regenerative Biomaterials, 2021, 8(4):rbab031.SCI

[10]  Yan Huang, Xiaoying Lü*, Rong Chen and Ye Chen. Comparative study of the effects of gold and silver nanoparticles on the metabolism of human dermal fibroblasts. Regenerative Biomaterials, 2020, 7(2):221-232.SCI

[11]  Yan Huang, Xiaoying Lü, Xiaoqiang Lü. Cytotoxic Mechanism for Silver Nanoparticles Based High-Content Cellomics and Transcriptome Sequencing. Journal of Biomedical Nanotechnology, 2019,15(7): 1401-1414.SCI

[12]  Yan Huang, Xiaoqiang Lü, and Xiaoying Lü. Study of key biological pathways and important microRNAs involved in silver nanoparticles induced cytotoxicity based on microRNA sequencing technology. Journal of Biomedical Nanotechnology, 2018,14: 2042-2055SCI

[13]  Yan Huang, Xiaoying Lü, Yinghua Qu, Yamin Yang, Si Wu. MicroRNA sequencing and molecular mechanisms analysis of the effects of gold nanoparticles on human dermal fibroblasts. Biomaterials 2015, 37:13-24SCI

[14]  Yan Huang, Xiaoying Lü, Jingwu Ma. Toxicity of Silver Nanoparticles to Human Dermal Fibroblasts on MicroRNA Level. Journal of Biomedical Nanotechnology, 2014, 10(11), 3304-3317.SCI

[15]  Yan Huang, Xiaoying Lü. The Influence of Silver Nanoparticle-Induced Oxidative Stress on MicroRNA Expression and Cytotoxicity. Science of Advanced Materials. 2014, 6(8), 1907-1918SCI

[16]  Yan Huang, Xiaoying Lü, Weiping Qian, Zuming Tang, Yinping Zhong. Competitive protein adsorption on biomaterial surface studied with reflectometric interference spectroscopy. Acta Biomaterialia, 2010, 6(6):2083-2090SCI

[17]  Huang Yan, Lü Xiaoying, Ma Jingwu, Huang Nan. In vitro Investigation of Protein Adsorption and Platelet Adhesion on Inorganic Biomaterial Surfaces. Applied Surface Science, 2008, 255(2): 257-259.SCI

参编专著:

[1]     Xiaoying Lü, Yan HuangSilver Nanoparticles for Antibacterial Devices: Biocompatibility and Toxicity》第10“Evaluating the interactions of silver nanoparticles and mammalian cells based on biomics technologies”,英国CRC出版社,2017年。